Donations of clothes, toys and other items are being sought to help the family affected by the house fire in Wentworth Road, Rugby.
A drop-off point has been created at the Benn Partnership Centre, in Railway Terrace, Rugby (CV21 3HR 01788 553033).
Donations can be dropped off from Monday to Friday between 9am and 5pm.
The collection has been set up following discussions between the centre and members of the family of the woman and children affected by the fire.
A fire officer described the interior of property as being completely damaged by smoke, and the ground floor as being 100 per cent destroyed by fire.
A spokesman for the centre said: "We are collecting donations of clothes, shoes, furniture, toys... anything for the family affected by the devastating fire at Wentworth Road.
"Any donations, however small, will be extremely helpful to the family who have lost everything."
Clothes sizes wanted are: girl's size 9-10 years; boy's size 5-6 years; boy's 11-12; and women's size 8.
The emergency services have praised the response of the local community during the incident as people helped the family, and following on during the investigation.
A Gofundme page has been set up to aid the victims of the fire, with the creator stating all the children's Christmas presents were destroyed in the fire.
The fire broke out shortly before 3am on Thursday, November 15 in a semi-detached house in Wentworth Road, Rugby.
A five-year-old boy injured in the fire remains in a critical but stable condition in hospital. A woman and two other children continue to be treated in hospital for burns and smoke inhalation
Police have said they have arrested a 21-year-old man from Rugby was arrested on suspicion of arson with intent to endanger life.