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Breakthrough drug trial in fight against Huntington’s disease

Results from a “ground-breaking” drug trial have offered new hope to people with Huntington’s disease.

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orensic officers at the scene of a house fire on Jackson Street (Peter Byrne/PA)

Five quizzed over suspected murder of three children who died after house fire

Five people are being questioned over the suspected murder of three children who died after a house fire.

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Traffic is forced to drive in one lane as snow covers most of the A470 dual carriageway past Merthyr Tydfil, Wales (Ben Birchall/PA)

Deep freeze continues as UK could see coldest night of the year

Treacherous ice and snow continued to cause travel disruption across the country as forecasters warned that the coldest night of the year could be in store.

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Keith Chegwin has died after battling a progressive lung condition (Ian West/PA)

Swap Shop stars mourn Keith Chegwin after his death at 60

Keith Chegwin’s Multi-Coloured Swap Shop co-stars have paid tribute to him after his death at the age of 60.

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Forensic officers at the scene of  the house fire on Jackson Street in Worsley (Peter Byrne/PA)

Five quizzed over suspected murder of three children who died after house fire

Five people are being questioned over the suspected murder of three children who died after a house fire.

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The driver failed to stop at the scene and the woman was subsequently hit by a second lorry and two cars (PA)

Four drivers sought by police after woman dies in ‘multiple hit-and-run’

A woman has died after being struck by two lorries and two cars in a suspected multiple hit-and-run, police said.

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Theresa May announced £140 million of new funding to help the world's poorest communities build resilience to extreme weather events (PA)

May marks Paris climate change gathering by increasing global funding

As international leaders gather in Paris to mark the second anniversary of the climate change plan agreed in the French capital in 2015, Theresa May has announced millions of pounds of UK funding to help those worst affected.

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Runners pass Manchester Town Hall during The Great Manchester Run (PA)

The UK’s economic divide between North and South to widen, report says

The economic gap between the North and South will keep expanding until 2020 as efforts to rebalance the UK economy fall short, according to new research.

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Theresa May gave a statement to MPs about progress in the negotiations (Rick Findler/PA)

May: Divorce bill offer off table without UK agreeing partnership with Brussels

Theresa May has said Britain’s offer for its divorce bill with the EU will be off the table if the UK does not agree a future partnership with Brussels.

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What the papers say - December 12

What the papers say – December 12

Social media giants and snowflakes are making the headlines in Tuesday’s papers while the public enquiry into the Grenfell Tower fire is also featured on the front pages.

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Nazanin Zaghari-Ratcliffe

Johnson had ‘worthwhile’ Iran meetings in bid to secure release of jailed Briton

Boris Johnson has said he had “worthwhile” meetings in Iran to secure the release of Nazanin Zaghari-Ratcliffe and that the Government “will leave no stone unturned in our efforts”.

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A couple take a rest on the Malvern Hills as the sun sets over Herefordshire (David Davies/PA)

Bitter spell continues as temperatures plummet as low as -13C on coldest night

Britain had its coldest night of the year as vast swathes of the country fell below freezing – with -13C (8.6F) recorded in Shropshire.

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Fire crews are at the scene in Allington Drive, Birstall (PA)

Woman in critical condition after ‘gas blast’ destroys house

A woman is in a critical condition in hospital after a home was destroyed in a suspected gas blast.

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Sir Richard Branson (PA)

Sir Richard Branson reignites feud with BA boss over £1 million bet

Sir Richard Branson has fanned the flames of a long-running feud with the boss of British Airways, calling on Willie Walsh to settle a “very public and painful” £1 million bet.

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Keith Chegwin (Yui Mok/PA)

Keith Chegwin dies aged 60 after battling lung condition

TV presenter Keith Chegwin has died at the age of 60 following a long illness, his family has said.

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Police have been combing a landfill site in Milton, Cambridgeshire ( Joe Giddens/PA)

No trace of missing RAF gunner Corrie McKeague as landfill search ends

The landfill search for missing RAF gunner Corrie McKeague has concluded without finding any trace of him.

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An engineer walks through a Victorian built sewer system (Gareth Fuller/PA)

Wipes form 93% of sewage blockages, study finds

Wipes make up to 93% of material causing sewer blockages, according to a study by Water UK.

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Keith Chegwin death

Four of Keith Chegwin’s best moments

Keith Chegwin had a varied career, from presenting Swap Shop to appearing on Celebrity Big Brother.

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The suspect was not found to be carrying any offensive weapons (Anthony Devlin/PA)

Man held after trying to climb into Buckingham Palace

A man has been arrested on suspicion of trespass after attempting to climb a wall into Buckingham Palace.

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The Square Mile faces an exodus of banking jobs in the wake of Brexit (PA)

City to see 10,500 jobs shift to EU because of Brexit

Firms in the Square Mile are planning to shift 10,500 jobs out of Britain by the first day of Brexit as the economic reality of the vote begins to bite.

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