Men will be digging out their best frocks for fun and frolics in Sheep Street on Tuesday.
Spectators may do a double take when the annual ladies’ pancake race takes place in the town.
More fun runners are needed to dress up and take part in the event, held by Rugby Rokeby Lions.
Men in drag are invited to take part in the event, but only the women can collect the trophies.
Funds will go to William Lamont and Lions’ Charities.
Two-year-old William was diagnosed with a rare genetic condition known as Kleefstra Syndrome a year ago. There were only 75 known cases in the UK as recently as 2009.
Kleefstra Syndrome is a condition in which a tiny piece is missing from near the end of one of the body’s 46 chromosomes which is believed to cause the major symptoms of the syndrome.
At present William weighs 16kg, which is some 20 per cent above average for his age, and has outgrown all conventional pushchairs which means his devoted parents Emma and Paul, have to physically carry him wherever they go and are in urgent need of a pushchair. Lion Mike Swan said: “We are trying to raise £2,000 or more to buy a specialised pushchair for William so that he will be able to be transported as needs be and be more involved in everyday activities, instead of having to miss out on opportunities for day-to-day contact with others.”
The event starts at noon at Rugby Hotel, Sheep Street.
Call (01788) 521205 for more.