London Midland and Virgin trains from Rugby to London have been disrupted due to a fire in Harrow.
London Midland is advising its passengers not to travel between Milton Keynes and London Euston today after a major fire at a commercial property in Harrow means mainline train services cannot currently run to the capital.
A spokesman for London Midland said: "While the emergency services are dealing with the fire it simply isn't possible to run trains through the area."
London Midlands state the fire closed the mainline around 12:30am.
London Midland is reminding passengers delayed by 30 minutes or more to claim compensation.
Details can be found on the company's website
Information of London Midland service disruption can be found here.
Information of Virgin services affected can be found here.